The duration of treatment with enzalutamide (brand name Xtandi) for patients with prostate cancer can vary depending on several factors, including the stage of the cancer, the patient's overall health, and how well the cancer is responding to the drug. However, here are some general guidelines:

1. Metastatic castration-resistant prostate cancer (mCRPC)
First-line treatment: For patients with metastatic castration-resistant prostate cancer (mCRPC), enzalutamide is usually given until the cancer has progressed, that is, until there is evidence that the cancer is no longer responding to the drug (such as an increase in PSA levels or a new metastasis).

Treatment duration: Some patients may remain on enzalutamide for months to years, particularly if they respond well to treatment, but it will be discontinued if progression occurs or significant side effects occur and Enzalutamide Price in Malaysia.

2. Non-metastatic castration-resistant prostate cancer (nmCRPC)

In the case of non-metastatic CRPC, enzalutamide may be used to delay the progression of metastatic disease. Patients may remain on enzalutamide for several months or years, depending on their individual response.

3. Adverse effects

If a patient experiences significant side effects (such as fatigue, seizures, or cardiac problems), treatment may need to be adjusted or discontinued as quickly as possible.

4. Combination therapy

In some cases, enzalutamide may be used in combination with other treatments, such as androgen deprivation therapy (ADT), and this may affect the duration of treatment. When used in combination, the overall treatment plan may change based on the patient's response and tolerability.

5. Discontinuation Criteria

Enzalutamide is typically discontinued when disease progression is observed, when the patient develops intolerable side effects, or if the patient's overall condition necessitates a change in therapy.

Ultimately, the duration of treatment is individualized and determined by the treating oncologist based on continued assessment of treatment response and side effects. Regular follow-up appointments and tests (such as PSA levels, imaging) are used to monitor the effectiveness of enzalutamide and make any necessary adjustments and Enzalutamide Price in Philippines.